Saturday, 5 April 2014

Chromosomes Alterations and Evolution

As we know, chromosomes alterations in human being have usually negative effects, causing diseases, sterile individuals or even death.  However, many species not only survive with these alterations but they can evolve from them. These alterations are a type of mutation, which is source of changes in the genome, leading to genome evolution (Reece et al., 2011). I going to explain how some types of chromosome alterations contribute to the evolution: Polyploidy (widely common in plants and rare in animals) and alterations of chromosome structure.
             Duplication of entire chromosome sets is result of accidents in meiosis that produce diploid gametes. According to Freeman and Herron (2004), if an individual self-fertilize its produced male and female diploid gametes, it will originate a polyploid organism. If this organism can self-fertilize or mate with another poplyploid, it is established a tetraploid population.  This event is important in evolution because if the tetraploid population mates with their parental diploid population, they will originate triploid organisms, which are sterile due to the odd number of chromosome set. Therefore, this leads to branching off of a new species. Also, the extra sets can accumulate mutations that promote new functions of the extra genes, maintained by natural selection (Freeman and Herron, 2004). These events change the individual phenotype and the new population diverges further from their parental population.
          Another contribution to evolution is observed in alterations of chromosome structure. Researchers have noticed chromosome rearrangements comparing a species to another. For example, ancestral chimp chromosomes 12 and 13 seem to have fused end to end, forming the chromosome 2 of a human ancestor. Comparing some species, scientists find many duplications and inversions of large portions of chromosomes, as result of DNA breaks and incorrect rejoining during meiotic recombination. These events might have accelerated about 100 million years ago, contributing to the generation of new species (Reece et al., 2011).

REFERENCE LIST:
Freeman, S. & Herron, J.C. (2004) Evolutionary Analysis. 3th ed. Pearson Prentice Hall. United States of America. p 124.

Reece, J. B.; Urry, L. A.; Cain, M. L.; Wasserman, S. A.; Minorsky, P. V.; Jackson, R. N.(2011) Campbell Biology. 9th ed. Pearson Australia Group. p 446.

2 comments:

  1. Chromosomal alterations are very interesting. Can you provide an example of an organism that is polyploidy? Do humans show any alterations in chromosome structure within the species, as well as between humans and primates? These two topics are great areas for future research as there are so many unanswered questions.

    ReplyDelete
  2. Yes. Nearly hald of all angiosperm species are polyploid. One example is the plant species Hibiscus rosa-sinensis.
    There is chromossome alterations in humans usually causing diseases or even cancers. An example is the syndrome Cri du Chat (Cry of the Cat), a deletion in chromosome 5. As I said at the last paragraph, it is seen some evidences of chromosome structure during evolution from primates to humans.
    I may talk more about the effects of these alterations on phenotype later.

    ReplyDelete